Wednesday, July 1, 2020

ULTIMATE database is now accessible through Pharmit!

Mcule’s new ULTIMATE database has been recently made available on Pharmit’s virtual screening platform. Scientists can now utilize this excellent synergy to use the platform for carrying out structure-based pharmacophore modeling and virtual screening. With 122 million novel compounds, ULTIMATE is an excellent database to search when scaffold hopping, navigating out of patented space, or identifying new chemotypes.

“We are very happy that Pharmit has integrated ULTIMATE, and hope that the whole scientific community will benefit from this integration” - Robert Kiss, CEO of Mcule

“ULTIMATE is an excellent complement to our platform, Pharmit users will surely find it useful for their projects” - David Koes, Assistant Professor at University of Pittsburgh

About Mcule:
Mcule is a chemical marketplace for drug discovery with services based around small-molecule compound sourcing. While the traditional Mcule database aggregates chemical suppliers to cover the “in stock” chemical space, ULTIMATE contains 122 million novel compounds that can be delivered with an 80% success rate in 2-6 weeks and have fixed prices. The company also provides solutions for sample preparation, solubility inspection, and independent QC analysis.

About Pharmit:
Pharmit provides an online, interactive environment for the virtual screening of large compound databases using pharmacophores, molecular shape, and energy minimization. It enables users to search for small molecules based on their structural and chemical similarity to another small molecule, with the goal of identifying those that bind to a target molecule (typically a protein receptor or enzyme).

Please visit the Pharmit and ULTIMATE website for more information:

Tuesday, April 28, 2020

Project-specific subsets of the ULTIMATE database are now available from Mcule!

As many of you know, we have recently released our database of 122 million completely novel and synthetically feasible compounds, the ULTIMATE database. https://ultimate.mcule.com/ 

Our cheminformatic team has created focused ULTIMATE libraries to jumpstart your project without the need to search in the full chemical database.

For a detailed description and to access the ULTIMATE subsets, please reach out to us at support@mcule.com

Thursday, April 9, 2020

Collection of 122 million novel and synthetically accessible compounds

Mcule introduces the 1st release of the ULTIMATE database.

Mcule has officially launched its own developed database of novel and synthetically accessible compounds.

The 1st version of the ULTIMATE database contains over 122 million compounds with known prices, 80% synthetic success rate and 2-6 weeks delivery time. ULTIMATE is based on robust reactions and off-the-shelf building blocks of our supplier partners such as HTS Biochemie, Key Organics and Life Chemicals.

Our web application provides a comfortable way to discover this novel chemical space online. Please visit: https://ultimate.mcule.com/

If you want to download the ULTIMATE database, reach out to us at support@mcule.com.

Monday, March 23, 2020

Free compounds from Mcule, designed against COVID-19

Mcule and its partners are contributing to the work of the scientific community against COVID-19 by carrying out computational studies to identify potentially effective compounds against relevant targets (like the spike protein of SARS-CoV-2) and shipping them free of charge for research labs that are working on a SARS-CoV-2 related project.

If you work at a research group / CRO that is capable of carrying out experimental screening against SARS-CoV-2, please reach out to us with a brief description of your company/research project.

This is an urgent call, please write to us at info@mcule.com if interested!