As many of you know, we have recently released our database of 122 million completely novel and synthetically feasible compounds, the ULTIMATE database. https://ultimate.mcule.com/
Our cheminformatic team has created focused ULTIMATE libraries to jumpstart your project without the need to search in the full chemical database.
For a detailed description and to access the ULTIMATE subsets, please reach out to us at support@mcule.com
Mcule introduces the 1st release of the ULTIMATE database.
Mcule has officially launched its own developed database of novel and synthetically accessible compounds. The 1st version of the ULTIMATE database contains over 122 million compounds with known prices, 80% synthetic success rate and 2-6 weeks delivery time. ULTIMATE is based on robust reactions and off-the-shelf building blocks of our supplier partners such as HTS Biochemie, Key Organics and Life Chemicals.
Our web application provides a comfortable way to discover this novel chemical space online. Please visit: https://ultimate.mcule.com/
If you want to download the ULTIMATE database, reach out to us at support@mcule.com.
Mcule and its partners are contributing to the work of the scientific community against COVID-19 by carrying out computational studies to identify potentially effective compounds against relevant targets (like the spike protein of SARS-CoV-2) and shipping them free of charge for research labs that are working on a SARS-CoV-2 related project.
If you work at a research group / CRO that is capable of carrying out experimental screening against SARS-CoV-2, please reach out to us with a brief description of your company/research project.
This is an urgent
call, please write to us at info@mcule.com if interested!
As an online drug discovery platform, we have been helping
pharmaceutical companies in the early phase of research processes. Although our
compound sourcing solution and advanced computational tools have been
continuously found helpful in the pharmaceutical industry, we are convinced that our
capabilities could also be advantageous for academic research scientists.
Mcule is the largest chemical webshop with more than 35 M
compounds. In addition our platform contains multiple computational tools for
searching and virtual screening, e.g. large-scale docking, scaffold hopping, diversity selection
and property calculator. We intended to make our services easily available to
use in academic research projects. We therefore introduced a subscription plan for academic researchers to get access to our advanced
tools and higher limits for a reasonable price, even for short-term (1,3,6-month)
projects.
Moreover, with the help of our online price optimization algorithm one can easily finalize the virtual screening procedure by ordering the selected compounds. The best price and the fastest delivery time quotes are automatically calculated, and it is up to you which one you select. After generating a quote an effective price of products and suppliers will be displayed which could ease on your budget by removing the largest contributions to the price.
Have you ever dreamt about the possibility to have access to the vast majority of molecules being relevant in the pharmaceutical
industry? Now it is finally becoming
real. Mcule has introduced the idea of a super-sized chemical library and
announced the start of the so-called ULTIMATE DATABASE PROJECT.
Our aim is to create a database of 500 million compounds, which would
include completely novel molecules predicted to be synthesizable but not
yet synthesized. Compounds should meet the following standards to be considered in the Ultimate database: minimum of 80% success rate of synthesis, maximum of 6-week delivery time and fixed prices.
A database of this size has yet to be made applicable for everyday use, and its integration with computational tools has always been a very
challenging task due to the high demands of IT infrastructure to handle such a large size. However, using the online interface in our website
one can easily access the full database, filter among the compounds, generate a
quote, and complete the order. Thus, it has never been easier to identify more
hits, eventually leading to reduced time and costs needed
to be invested into the discovery of a new drug candidate.
By ourselves we wouldn’t be able to achieve our goals, therefore we seek
supplier and custom molecular synthesis partners who would like to contribute to this great cause.
As for suppliers, our
subscription form can be found here.
For users, registration for an early access is available here. Please see our website for more information, https://mcule.com/ultimate-project/.
